Super refractory status epilepticus pdf merge

It is associated with high rates of mortality and morbidity associated serious brain damage, respiratory infections, feeding problems. Refractory status epilepticus seizure european journal of epilepsy. Pdf pharmacotherapy for status epilepticus researchgate. Refractory to two antiepileptic agents and general anesthesia treatment for 24 hours. Pediatric intensive care treatment of uncontrolled status epilepticus. Andrew cole, md of massachusetts general hospital and harvard medical school explains superrefractory status epilepticus. Pharmacotherapy for status epilepticus springerlink. Many of the recommended doses or targeted therapeutic levels are higher than referenced in the literature and based upon expert opinions at nyph. Common intravenous agents such as diazepam, lorazepam, midazolam, and phenytoin used to treat rse have frequent problems with toxicity or efficacy 35.

Treatment of refractory and superrefractory status. Pdf refractory and superrefractory status epilepticus. Table 2 medications used for refractory status epilepticus rse. Treatment of refractory and superrefractory status epilepticus ncbi. Pdf treatment of established status epilepticus researchgate. Status epilepticus and beyond acute and critical care.

Ketamine for the treatment of refractory status epilepticus. Management of superrefractory status epilepticus with. This definition and the treatment guidelines have been subsequently revised. Superrefractory status epilepticus explained youtube. Refractory status epilepticus rse is continued seizures after the failure of two or more aeds. Pharmacotherapy for pediatric convulsive status epilepticus.

Pediatric status epilepticus treatment algorithm combining current guidelines. Transitioning treatment from status epilepticus to super refractory status epilepticus david roy, pharmd pgy1 pharmacy resident. The treatment of superrefractory status epilepticus. More likely to be due to acute encephalitis 30516601. The term superrefractory status epilepticus was introduced during the londoninnsbruck colloquium on status epilepticus in 2011 and refers to status epilepticus that continues or recurs 24 h or. Pdf status epilepticus is the most severe form of epilepsy, with a high.

Refractory and superrefractory status epilepticus indian pediatrics. Generalized convulsive status epilepticus emcrit project. Status epilepticus superrefractory fires epilepsy anesthesia pediatric. This is a pdf file of an unedited manuscript that has. Refractory to first and secondline antiepileptic agents. Srse carries a high risk of morbidity and a high mortality rate ranging from 23 to 57% 2, 3. Superrefractory status epilepticus superrse refers to drugresistant status.

Refractory status epilepticus is defined as status epilepticus. Status epilepticus, refractory status epilepticus, and super. Guidelines for the evaluation and management of status epilepticus. Management of refractory status epilepticus in adults. Incidence and mortality of superrefractory status epilepticus in adults. Super refractory status epilepticus is a medical emergency neces sitating aggressive treatment for early control seizures.

With the use of the proposed protocol, combining midazolam and phenytoin. Srse is defined as status epilepticus that continues 24 h or more after the onset of anesthesia, including those cases in which the status epilepticus recurs on the reduction or withdrawal of anesthesia. Super refractory status epilepticus is a status epilepticus that continues for. Super refractory status epilepticus is defined as status epilepticus that continues or recurs 24 h or more after the onset of anaesthetic therapy, including those cases where status epilepticus.